Tirz works on two different hormonal receptors: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). You may have heard of GLP-1 from other weight loss injections. GLP-1 helps to regulate blood sugar levels, which in turn talks to the brain to make you feel less hungry and prevent cravings. It also slows down the emptying of the stomach to keep you feeling fuller for longer. GIP regulates energy balance in brain and fat cells, enhancing the GLP-1 effect of suppressing your appetite and improving sugar control. By mimicking the effects of both these naturally occurring hormones, Tirz has been shown to have greater weight loss potential than medicines that work on GLP-1 alone.
Dosage Protocol:
To allow your body to get used to the medicine and have the best chance for long-term success, you should follow the gently increasing dosage schedule as instructed.
Most beginner-friendly protocols follow this conservative escalation model:
Week 1–4: 2.5 mg once weekly (starting dose)
Week 5–8: 5 mg once weekly
Optional Increase: 7.5 mg → 10 mg → up to 15 mg weekly (only as needed).
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